Grotesquerie

...a significant hurdle is the efficient delivery of RNA molecules

to cancer cells while avoiding off-target effects.

It's unstable in the body.

And then there's a high likelihood of immune responses.

The answer, I believe,

is in developing ultrasophisticated nanoparticles

to encapsulate and protect RNA molecules, improving their stability.

Um...

Let's, uh, pick this up next session, guys, okay?

It's good of you to see me, Doctor. I didn't think you would.

You're the last holdout within your mother's inner circle.

Well, Dr. Witticomb, I'm not really sure what good I'd be,

or even what your approach to her therapy is.

I mean, how exactly am I important to this process?

It's controversial, what I do. Neuroimaging.

Functional MRI and EEG show patterns of brain activity

that look like aspects of dream activity.

So she was locked in, rather than comatose?

She was in a liminal state, and at times, very aware of her dreams.

She has an extraordinary recall of them.

And if we can advance the science of communicating to people in comas,

my hope is we can find ways to awaken them.

Well...

I'd feel like an asshole if I didn't help.

Thanks. I should warn you, it's not an enjoyable process.

You'll hear things you won't like.

Do you mind if I record you?

Fire away.

In her dream, you were in, um, some sort of reality television show.

What? Television? I hate television.

The only thing I watch is, like, The Wire on a loop.

So what's the name of the show I was on?

Half-Ton Trauma.

A show in which morbidly obese people...

Try to lose weight.

- I told you this would not be easy. -

Well, that woman isn't easy.

Your star patient.

- - To center.

Okay.

Good. Good. Okay. It's okay.

It's okay. Just try it again.

Good. Just...

- - Oh.

- Shit. - It's okay.

I couldn't do this before I was in a coma.

Jesus Christ.

What the fuck do you want?

Just wanna see how you're doing.

Fuck off.

You tried to kill me. I heard all of it. All of it!

- Lois, you hallucinated... - Mm-mmm.

- ...half of what you heard. - Mm-mmm.

I wasn't trying to kill you. I was trying to keep you alive.

I-I am done with all of this. All of you. I... I wanna go home.

I just wanna go.

Okay. Let me just...

It's okay.

- It's okay. - Don't touch me.

- Okay. Just reach out... - Don't touch me.

Paddles!

- Mom, you better fight. - Clear!

- I need Adrenalin. - You fucking bitch. Fight!

You know, I never understood why you're such a royalist.

Look at them, disasters in the making.

Di, filled with terror and hope.

Charles, grim and loving someone else.

I'm gonna roast a chicken, yeah?

I could use a prep chef.

Um...

I don't really want to move.

I'm not hungry.

It's fine. Yeah.

I could use the activity, actually.

Maybe you'll be hungry by the time it's ready, huh?

- Hmm. - Yeah.

Always think of the future, even if it's only in one-hour increments.

That's why I like the royal family.

They're always thinking about the future,

but always in relation to the traditions of the past.

I guess we need all the rituals we can get.

Like roasting a chicken.

I'm not staying in it.

She's awake. I'm divorcing her.

I'm done.

Can you do that?

I mean, can you live with that decision?

You stayed for all of it.

Why would you stay with me anymore if I didn't leave now?

The ritual of it.

- You being here. - Hmm.

And, you know, I think that maybe this is the place

where you're really at peace, right?

Don't do it because you think you'll lose me if you don't.

I started the process to get her out of my life.

I saw the lawyer, Mr. Berger.

He's drawing it up.

I hope she has some sort of life after all this.

That she realizes that to stay together is impossible

when you know too much about who you both are.

She knows I want her to die.

I whispered in her ear during visits. First it was, "You can go."

Then it progressed to...

Please just fucking die.

She heard everything, the doctor said.

Can you imagine the level of stamina and control, to be in a coma

and never turn off your fucking satellites and antennae?

Charles.

I always admired him.

She was clearly mentally ill.

He was clearly hardwired for duty.

He kept going.

Living in his duty.

Finally finding happiness with the woman he always loved.

- I think I'll eat now. -

Interview one with Chief of Police Megan Duval.

So you would not describe your relationship with Detective Tryon

as adversarial?

No. She was a mentor to me.

She was thrilled when I became chief. I listened to her. I took her counsel.

And what about the case of Andrea Salana?

How do you think she handled that?

She blew it. She totally blew it.

She should have helped that woman way earlier,

and I was very up-front about it.

Go on.

It was shit police work, and she was guilty.

She was slipping and she was tired, and, um...

and I fucking let her know it.

It did result in some tension, but she was always very up-front with me,

and I had to pay her the same respect.

We did have one fight right before her retirement party

where I let her know how I felt.

She had sudden qualms about actually leaving,

and I said, "Hey, babe, it's time."

I had made this punch.

What color was the punch?

Purple.

Violet, really.

It was awful.

- Go to hell. - Cheers.

Thank you, Chief. One last thing.

The color of the punch, was it more like...

the color of a bruise?

Yes.

Very much so.

And were there bruises on Andrea Salana's body when she was found dead?

Purple bruises?

She had been beaten to death. Yes.

She looked like a different species from all the bruising.

You're late.

I'm mad hungry.

Mmm.

Blood sugar must be low or something. I don't know.

I'm not in the mood for your shit, Justin.

I'll heat up the Chinese.

- -

Is this what you want?

Is it?

You know I'm gonna have a shiner from your fucking fist!

And they know you at the precinct.

Too many bruises, too many emotional crying calls.

You want me to just end this for you?

Is that what you want, Justin?

You don't have the fucking balls, Meg.

Just get the fuck out.

It's my house.

My house, my rules.

- - My...

Fine. Stay then.

- Enjoy dinner, you fuck. -

Fuck.

Fucking bitch!