Pure Genius

Previously on Pure Genius.

My mom hasn't been feeling well lately.

If you're really concerned about your mom, why don't you

just have a real and honest conversation with her?

Yeah, we don't do that.

Angie, your mom has cervical cancer.

Unfortunately, it's spread to her other organs

through her bloodstream.

I wish you'd mentioned that the Grim Reaper

was coming here to ruin our GSS trial.

I need more data from the animal models

for approval of a human trial.

The study wasn't approved.

I will not give up fighting for you.

I'm fighting for me.

: I might be running out of time, James.

Do you regret the decision you made back in Ohio?

Giving the boy with leukemia

the unapproved drug?

What the FDA doesn't know

can't hurt them.

Can't hurt me.

Oh, my God.

It worked.

Whoa. Whoa!

What's going on?

Fremont Jones, a new patient.

His oxygen level is low and his body temperature's dropping.

What's he being monitored for?

- A clotting disorder. Look at his body temp.

That's not a clotting issue.

And his oxygen sats are plummeting.

Wait, where is he?

On the Bay Bridge.

He's not on it.

He's under it. He's in the water.

Call the Coast Guard. Now.

W.

I didn't know if you were, um...

What was happening just then?

I was thinking.

Deeply.

James, I just, I want to let you know that over the next few days

I might be out of the hospital a bit.

Of course. Nothing wrong I hope.

No, no.

Just Julianna's coming today.

I wanted to ask her to move out here

once Luke leaves for college in the fall.

It's just something I...

- Your wife is here today? - Yeah, is that a problem?

No, not a problem, nothing we can't manage.

It will make what I need to tell you more complicated.

What is it?

I wasn't even sure if I was gonna tell you this,

but I just meditated on it, decided that you need to know

and not telling you will only make matters worse, so...

What is it?

Look.

Cyanotic and hypothermic on scene.

Estimated submersion time: six minutes.

Multiple extremity fractures

with an open tib-fib on the right.

And pressure's 60 over palp.

Bilateral breath sounds,

no pneumothorax, so he's hemorrhaging somewhere.

Yeah, but nothing external.

Then get him into a bay; it's probably internal.

Two liters NS bolus, then O-neg,

and I need a FAST ultrasound to look for a hemoperitoneum.

He's losing blood volume faster than we can replace it.

Oh, my God. - FAST positive.

Blood in Morison's pouch and left pericolic gutter.

- Ruptured spleen. - Lacerated liver.

He has a massive intra-abdominal hemorrhage.

He needs surgery now.

Yeah, but he's gonna bleed out before we get there.

The DARPA foam.

: Yeah.

All right, prep, clean the field.

Yes, doctor.

Field prepped.

On three.

One, two...

The foam should expand to keep him from bleeding out.

- It's working. - Yeah, for now.

But all we did was buy ourselves a little time.

Can't fix anything until we remove the foam,

and when we do...

Bleed out all over again.

I still don't understand why I need to check in.

Because we're running tests and you'll feel more comfortable

having your own room.

It's like a fish bowl.

Which is why we have this. Look, you can make this room

any setting that makes you comfortable.

Like this.

Okay, okay, that was just an idea.

How about this?

Now I just feel cold.

Really, Mom?

Why can't we have a normal hospital room?

With blue walls a-and curtains?

And that smell.

That awful smell?

It makes it feel like a real hospital.

It doesn't matter what's on the walls,

the important thing is you're here, so we can get you...

better.

You know, Mrs. Lee had cancer.

She went to UCSF, they cured her.

They are affiliated with the university.

Everyone here is the best in their field.

Your grandmother had cancer.

She drank this tea...

Mom, tea did not get rid of grandma's cancer,

and it won't fix you.

Look, UCSF, they're gonna give you a 50/50 shot.

My people, we're gonna make this go away, period. Gone.

So just pick a setting for the wall,

and let me do my job, okay?

: Come on.

You gave Louis the treatment

that's banned from human trials.

I acknowledge I made that executive decision.

That was not your decision to make.

: You saw him.

Couldn't speak or move, now he's walking,

he's talking, clearly he's thinking.

- Clearly. - (phone beeping)

Ah, great, my wife's arriving.

Okay, I think we need to keep her off-campus for the moment.

Oh, you think?

Look, W, I'm sorry, but you saw him.

He was, he was dying. I had to do something.

You realize what this could mean.

I realize what it means to you, yes,

but I don't think you realize what you did.

The FDA prohibited use of that drug in human subjects,

and it's only been a few days,

- so we don't know the side effects. - W...

And my wife was the one who explicitly...

- (chuckles) Julianna. - Julianna!

- Hi. - Wonderful surprise.

- Hi, honey. - Nice to see you.

- Hi, thank you so much for... - Hi.

...dropping everything and coming out here.

Well, it sounds like big things are happening.

Yeah, listen, you're really exhausted from that flight.

No, I'm not.

Yeah, and we have a really crazy day today.

- Our, um... - Angie.

Angie Cheng.

Oh, yeah, the tech guru?

Yeah, her mom just got a... terrible diagnosis.

Cancer.

Oh. Wow, I'm sorry.

So you can imagine it's just...

Right, okay.

So, well, we shouldn't have lunch, then, after all.

If that's okay.

Yeah, it's... of course, it's fine.

I, uh, I brought a lot of work.

I'll just, you know, I'll find a place

- to stay and... hang out. - Great.

- Or... - Yeah.

Or, um, you could work at our place

'cause we're gonna work really late tonight. - Yeah.

- Really late. - That's okay. I can wait.

The cab just left, so...

No problem, you know, to get you a car home.

Yeah.

Okay. Fine.

I, uh, I can work from your place.

- Yeah, good choice. - Great.

Yeah.

The patient fell off the Bay Bridge this morning.

- Jumper? - Painter.

Fremont Jones, known as "Free."

Ah, the graffiti artist, huh?

I know his work; he's brilliant.

Well, right now he doesn't have much hope.

We used the DARPA foam to stop his internal bleeding,

but when we remove it for surgery, he'll bleed out.

And there's another problem:

the water from the bay lowered his body temperature.

We tried to warm him up, but his toxic

metabolite production went through the roof.